Penile Injection Therapy for ED: Effectiveness, Side Effects and Safety

Penile injection therapy for ED is a relatively unpopular treatment option for men dealing with erectile dysfunction. While this treatment may not be for everyone, those who are willing to give it a try can enjoy erections and an improved sex life. The aim of this article is to provide you with all of the information you need on penile injection therapy for ED, including a look at the different types, effectiveness, side effects and safety of this treatment option.

What Is Penile Injection Therapy for ED?

Anti-ED injections are a treatment option made to help men achieve erections using injections to the side of the penis. Each injection can last for anywhere from 30 minutes to an hour or until the man climaxes. What makes some men apprehensive about this new and effective treatment is that self-injecting is required, meaning that a man must learn to inject himself in the penis so that he can use the treatment at home before having sex.

How Effective Is It?

Penile injection therapy using Caverject or Edex (also known as Alprostadil) has been proven to be extremely effective with over 80 percent of men achieving strong erections during their clinical trials. The injection takes effect within 5 to 15 minutes of injection and lasts long enough to enjoy a full sex experience and does not interfere with a man’s ability to orgasm.

Side Effects

The FDA has approved Penile Injection Therapy because it has shown little to no side effects. One of the only known side effects is a mild dull ache that occurs in approximately 37 percent of patients and only lasts a short time. In rare cases a man may suffer from priapism, which is a prolonged erection that is painful and remains rigid for anywhere from 4 to 8 hours. This is easily treated by a doctor and again, is quite rare. The only other known potential side effect is bruising at the sight of the injection, though this is more common if the same sight is injected multiple times.


Along with the noted side effects as discussed above, Penile Injection Therapy is known to be safe as the injections are comprised of 3 different drugs, all of which have been used for years to treat ED and other conditions safely even in considerably higher doses. It is understandable for someone to question how safe it can be to self-inject into such a delicate part of the body, but it has been reported time and time again that the injections are virtually painless thanks to the use of a very fine gauge needle. As well, the patient will be shown how to inject himself safely by the doctor and the dosage of the medication will be catered to his specific need so there are no excess levels of unneeded drug being administered. And, a proper medical history and checkup before starting the therapy will help to ensure that you can use this treatment safely.